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Division of Nephrology

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Publication

1. Lam MF, Leung JC, Lam CW, Tse KC, Lo WK, Lui SL, Chan TM, Tam S, Lai KN. Procalcitonin fails to differentiate inflammatory status or predict long-term outcomes in peritoneal dialysis-associated peritonitis. Perit Dial Int. 2008 Jul-Aug;28(4):377-84
2. Guo H, Leung JC, Lam MF, Chan LY, Tsang AW, Lan HY, Lai KN. Smad7 transgene attenuates peritoneal fibrosis in uremic rats treated with peritoneal dialysis. J Am Soc Nephrol 2007;18:2689-2703.
3. Lai KN, Leung JC, Chan LY, Saleem MA, Mathieson PW, Lai FM, Tang SC. Activation of podocytes by mesangial-derived TNF-alpha: glomerulo-podocytic communication in IgA nephropathy. Am J Physiol Renal Physiol 2008;294:F945-55.
4. Yung S, Chan TM. Anti-DNA antibodies in the pathogenesis of lupus nephritis--the emerging mechanisms. Autoimmun Rev 2008; 7: 317-321.
5. Wang AY, Lai KN. Use of cardiac biomarkers in end-stage renal disease. J Am Soc Nephrol 2008;19:1643-1652.
6. Chan WL, Leung JC, Chan LY, Tam KY, Tang SC, Lai KN. BMP-7 protects mesangial cells from injury by polymeric IgA. Kidney Int 2008;74:1026-1039.
7. Lui SL, Tsang R, Chan KW, Zhang F, Tam S, Yung S, Chan TM. Rapamycin attenuates the severity of established nephritis in lupus-prone NZB/W F1 mice. Nephrol Dial Transplant 2008; 23: 2768-76.
8. Yung S, Zhang Q, Zhang CZ, Chan KW, Lui SL, Chan TM. Anti-DNA antibody induction of protein kinase C phosphorylation and fibronectin synthesis in human and murine lupus and the effect of mycophenolic acid. Arthritis Rheum 2009; 60: 2071-2082.
9. Tang SC, Lam B, Lai AS, Pang CB, Tso WK, Khong PL, Ip MS, Lai KN. Improvement in sleep apnea during nocturnal peritoneal dialysis is associated with reduced airway congestion and better uremic clearance. Clin J Am Soc Nephrol 2009; 4:410-418.
10. Tam KY, Leung JC, Chan LY, Lam MF, Tang SC, Lai KN. Macromolecular IgA1 taken from patients with familial IgA nephropathy or their asymptomatic relatives have higher reactivity to mesangial cells in vitro. Kidney Int 2009;75:1330-1339.

Exceptional Publications

1. T.M. Chan, F.K. Li, C.S.O. Tang, R.W.S. Wong, G.X. Fang, Y.L. Ji, C.S. Lau, A.K.M. Wong, M.K.L. Tong, K.W. Chan, K.N. Lai, for the Hong Kong - Guangzhou Nephrology Study Group. Efficacy of Mycophenolate Mofetil in patients with diffuse proliferative lupus nephritis. New England Journal of Medicine, 2000; 343:1156-1162.
2. S. Tang, J.C.K. Leung, Katsushige Abe, K.W. Chan, L.Y.Y. Chan, T.M. Chan, K.N. Lai. Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells: an in vitro and in vivo study. Journal of Clinical Investigation 2003; 111: 515-527.
3. K.N. Lai, S.C.W. Tang, J.Y. Guh, T.D. Chuang, M.F. Lam, L.Y. Chan, A.W.L. Tsang, J.C.K. Leung. Polymeric IgA1 from IgA nephropathy upregulates synthesis and signal transduction of transforming growth factor- in human mesangial cell via the renin-angiotensin system. Journal of the American Society of Neprhology 2003; 14: 3127-3137.