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Research
Current
Research Interests of the Division
Lung
cancer
- Molecular
markers for early detection of bronchial dysplasia and lung
cancer in high risk population
-
Factors associated with progression/regression of pre-cancerous
lesion
Expression and functional assessment of antioxidants and biomarkers
in non-small cell lung cancer (NSCLC)
- Oncogenomics
and proteomics: microarray analysis in relation to clinical
parameters
-
Establishment and characterization of lung cancer cell lines
from Chinese patients, as models for studying gender and smoking
differences and for prediction of responses to therapeutic agents
- Endobronchial
treatment of early lung cancer
- Clinical
trials of chemotherapy and novel molecular targets as anti-cancer
agents for the treatment of NSCLC
- Epidemiology,
pathology and treatment of lymphoepithelioma-like carcinoma
of the lung
Obstructive
Sleep Apnea (OSA)
- Vascular
pathogenesis in OSA
- OSA
and insulin resistance/diabetes mellitus
- OSA
and metabolic syndrome
- Genetics
of OSA: Phenotype-genotype correlation of candidate genes
- Clinical
trials on treatment of OSA with CPAP, oral appliances and others
- Sleep
disordered breathing in renal failure
- Exploration
of clinical prediction models for OSA in Chinese
- Intermittent
hypoxia as a model for studying cellular and biochemical sequelae
of OSA
Asthma
- Simple
clinical tools in detecting under-treated asthma
- Genetics
of asthma: phenotype-genotype correlation of candidate genes
- Role
of oxidants/antioxidants and cytokine network in pathogenesis
and pathophysiology of asthma
- Role
of natural products having antioxidant or/and anti-inflammatory
effects in the treatment of asthma
Chronic
Obstructive Pulmonary Disease (COPD)
- Genetics
of COPD: phenotype-genotype correlation of candidate genes
- Role
of oxidants/antioxidants and cytokine network in pathogenesis
and pathophysiology of COPD
- Role
of natural products having antioxidant or/and anti-inflammatory
effects in the management of COPD
Animal
model of cigarette smoke (CS)-induced lung injury
- Cellular
and molecular mechanisms of oxidants/antioxidants and cytokine
network
- Airway
remodeling
- Role
of nicotine and nicotine acetylcholine receptors
- Screening
of natural products or Chinese herbal medicines in the management
of CS-induced lung injury
Bronchiectasis
- In
vitro studies of bacterial toxins from pseudomonas aeruginosa
(PA) or direct PA infection on airway epithelial cell culture
models for the signaling pathways in airway inflammation and
apoptosis
Other
airway and parenchymal diseases
- Role
of oxidative stress in the pathogenesis of silicosis
- Bronchiolitis
obliterans in organ transplant recipients
For
students wishing to undertake research degrees (eg PhD, MPhil)
please refer to the Postgradute page of the
Teaching and Traning homepage.
Enquires
on research interests for degrees (eg PhD, MPhil) in
the Division of Respiratory & Critical Care Medicine, please
contact : Prof Mary SM Ip thur Contact
us
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