Prof
TSE Hung Fat - William MW Mong Professor MBBS.
MD, PhD, FRCP (Lond, Edin, Glasg), FHKCP, FHKAM
Email:
hftse@hku.hk
Tel: 2255 3598
Fax: 2818 6304
Research
Interest
Basic and clinical
cardiac electrophysiology;
Novel non-pharmacological
therapies, such as medical devices and gene-based approaches
for cardiac arrhythmias;
Non-invasive assessment
of cardiovascular system, such as vascular ultrasound, CT
scan and MRI; and
Cardiovascular
regenerative medicine using gene-based and cell-based, including
adult, embryonic and induced pluripotent stem cells.
Selected
Publications
Tse HF, Kwong YL,
Lo G, Ho CL, Chan JKF, Yeung DW, Lau CP. Angiogenesis
in ischemic myocardium by intramyocardial autologous bone
marrow mononuclear cell implantation. Lancet 2003;361:47-49.
Tse HF, Reek S,
Timmermans C, Lee KLF, Geller C, Rodriguez LM, Ghaye B, Ayers
GM, Crijns HJGM, Klein HU, Lau CP. Pulmonary vein isolation
using transvenous catheter cryoablation for atrial fibrillation
without the risk of pulmonary vein stenosis. Am J Coll
Cardiol. 2003;42:752-758.
Liu B, Wang J,
Chan KM, Tjia WM, Deng W, Guan X, Huang J, Li KM, Chan JD,
Pei D, Pendas A, Lopez-Otin C, Tse HF, Hutchison C, Chen J,
Cao Y, Cheah KSE, Tryggvason K, Zhou Z. Genomic instability
in laminopathy-based premature aging. Nat Med 2005; 11:
780-785.
Tse HF, Xue T,
Lau CP, Siu CW, Wang K, Zhang QY, Tomaselli GF, Akar FG, Li
RA. A bio-artificial sinus node constructed via in vivo
gene transfer of an engineered pacemaker (HCN) channel reduces
the dependence on electronic pacemaker in a sick sinus syndrome
model. Circulation. 2006;114:1000-11.
Tse HF, Thambar
S, Kwong YL, Rowlings P, Bellamy G, McCrohon J, Thomas P.
Bastian B, Chan JKF, Lo G, Ho CL, Chan WS, Kwong RY, Parker
A, Hauser T, Chan J, Fong YT, Lau CP. Prospective randomized
trial of direct endomyocardial implantation of bone marrow
cells for therapeutic angiogenesis in severe coronary artery
diseases. Eur Heart J. 2007 Dec;28(24):2998-3005.