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Prof TSE Hung Fat - William MW Mong Professor
MBBS. MD, PhD, FRCP (Lond, Edin, Glasg), FHKCP, FHKAM

Email: hftse@hku.hk
Tel: 2255 3598
Fax: 2818 6304

Research Interest

  1. Basic and clinical cardiac electrophysiology;

  2. Novel non-pharmacological therapies, such as medical devices and gene-based approaches for cardiac arrhythmias;

  3. Non-invasive assessment of cardiovascular system, such as vascular ultrasound, CT scan and MRI; and

  4. Cardiovascular regenerative medicine using gene-based and cell-based, including adult, embryonic and induced pluripotent stem cells.


Selected Publications

  1. Tse HF, Kwong YL, Lo G, Ho CL, Chan JKF, Yeung DW, Lau CP. Angiogenesis in ischemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation. Lancet 2003;361:47-49.

  2. Tse HF, Reek S, Timmermans C, Lee KLF, Geller C, Rodriguez LM, Ghaye B, Ayers GM, Crijns HJGM, Klein HU, Lau CP. Pulmonary vein isolation using transvenous catheter cryoablation for atrial fibrillation without the risk of pulmonary vein stenosis. Am J Coll Cardiol. 2003;42:752-758.

  3. Liu B, Wang J, Chan KM, Tjia WM, Deng W, Guan X, Huang J, Li KM, Chan JD, Pei D, Pendas A, Lopez-Otin C, Tse HF, Hutchison C, Chen J, Cao Y, Cheah KSE, Tryggvason K, Zhou Z. Genomic instability in laminopathy-based premature aging. Nat Med 2005; 11: 780-785.

  4. Tse HF, Xue T, Lau CP, Siu CW, Wang K, Zhang QY, Tomaselli GF, Akar FG, Li RA. A bio-artificial sinus node constructed via in vivo gene transfer of an engineered pacemaker (HCN) channel reduces the dependence on electronic pacemaker in a sick sinus syndrome model. Circulation. 2006;114:1000-11.

  5. Lip GY, Tse HF. Management of atrial fibrillation. Lancet 2007; 370: 604-618.

  6. Tse HF, Thambar S, Kwong YL, Rowlings P, Bellamy G, McCrohon J, Thomas P. Bastian B, Chan JKF, Lo G, Ho CL, Chan WS, Kwong RY, Parker A, Hauser T, Chan J, Fong YT, Lau CP. Prospective randomized trial of direct endomyocardial implantation of bone marrow cells for therapeutic angiogenesis in severe coronary artery diseases. Eur Heart J. 2007 Dec;28(24):2998-3005.

 

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