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Prof WONG Chun Yu, Benjamin - Simon KY Lee Professor MBBS (HK), MD (HKU), PhD (HKU), MRCP (UK), FHKCP, FHKAM (Medicine), FRCP (Lond), FRCP (Glasg), FRCP (Edin), FACG, FACP. Email: bcywong@hku.hk Tel: 2255 4049 Fax: 2904 9443

Research Interest

1. Helicobacter pylori: epidemiology, diagnosis, therapy, relationship to gastric cancer.

2. Gastric, colon and pancreatic cancer (clinical): prevention, screening, therapy, and clinical trials.

3. Gastric and colon cancer (basic): apoptosis, gene therapy, cancer stem cell.

4. Gastro-esophageal reflux disease and functional dyspepsia: epidemiology, therapy and clinical trials
   
   
   

Selected Publications

1. Chey WD, Wong BC, Practice Parameters Committee of the American College of Gastroenterology. American College of Gastroenterology Guideline on the management of Helicobacter pylori infection. Am J Gastroenterol 2007; 102(8): 1808-25

2. Wang J, Yang Y, Xia HH, Gu Q, Lin MC, Jiang B, Peng Y, Li G, An X, Zhang Y, Zhuang Z, Zhang Z, Kung HF, Wong BCY. Suppression of FHL2 expression induces cell differentiation and inhibits gastric and colon carcinogenesis. Gastroenterology 2007; 132(3): 1066-76.

3. Zou B, Chim CS, Zeng H, Leung SY, Yang Y, Tu SP, Lin MC, Wang J, He H, Jiang SH, Sun YW, Yu LF, Yuen ST, Kung HF, Wong BC. Correlation between the single site CpG and expression silencing of the XAF1 gene in human gastric and colon cancers. Gastroenterology 2006; 131(6): 1835-43.

4. Tu SP, Cui JT, Liston P, Xu R, Jiang XH, Lin MCM, Zhu YB, Zou B, Jiang SH, Wong WM, Yuen MF, Lam SK, Kung HF, Wong BCY. Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant. Gastroenterology 2005; 128(2): 361-75.

5. Wong BCY, Lam SK, Wong WM, Chen JS, Zheng TT, Feng RE, Lai KC, Hu WHC, Yuen ST, Leung SY, Fong DYT, Ho J, Ching CK, Chen JS and the China Gastric Cancer Study Group. Helicobacter pylori eradication to prevent gastric cancer in a high-risk region in China: A randomized controlled trial. JAMA 2004; 291(2): 187-194.

6. Wang WH, Huang JQ, Zhang GF, Lam SK, Karlberg J, Wong BCY. Non-steroidal anti-inflammatory drug use and the risk of gastric cancer: A systematic review and meta-analysis. J Natl Cancer Inst 2003; 95(23): 1784-91.

Key Offices

1. Vice President of Hong Kong Society of Gastroenterology

2. Vice Chairman of the Hong Kong Scientist Association

3. Member of Colorectal Cancer Screening Committee of the World Organisation of Digestive Endoscopy (OMED)

4. Member of Guideline and Publication Committee of the World Gastroenterological Organisation (WGO-OMGE)

5. Coordinating editor, Journal of Gastroenterology and Hepatology