Home > Staff

Dr YUNG Sou Ying, Susan Bsc Tech (Hons), PhD Email: ssyyung@hku.hk Tel: 2255 3032 Fax: 2872 5828

Research Interest

1. Mesothelial cell biology and peritoneal dialysis

2. Immunopathogenesis of lupus nephritis

3. Matrix protein synthesis and fibrosis in kidney diseases
   
   
   

Selected Publications

1. Yung S, Chau MKM, Zhang Q, Zhang CZ, Chan TM. Sulodexide decreases albuminuria and regulates matrix protein accumulation in C57BL/6 mice with streptozotocin-induced type I diabetic nephropathy. PLoS ONE, 2013; 8: e54501 [impact factor: 4.092].

2. Cheung LW, Yung S, Chan TM, Leung PC, Wong AS. Targeting gonadotropin-releasing hormone receptor inhibits the early step of ovarian cancer metastasis by modulating tumor-mesothelial adhesion. Mol Ther 2013; 21: 78-90 [impact factor: 6.873].

3. Lui SL, Yung S, Yim A, Wong KM, Tong KL, Wong KS, Li CS, Au TC, Lo WK, Ho YW, Ng F, Tang C, Chan TM. A combination of biocompatible peritoneal dialysis solutions and residual renal function, peritoneal transport, and inflammation markers: a randomized clinical trial. Am J Kidney Dis 2012; 60: 966-975 [impact factor: 5.434, citations: 1].

4. Yung S, Cheung KF, Zhang Q, Chan TM. Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis. J Am Soc Nephrol 2010; 21: 1912-1927 [impact factor: 9.663, citations: 8].

5. Yung S, Zhang Q, Zhang CZ, Chan KW, Lui SL, Chan TM. Anti-DNA antibody induction of protein kinase C phosphorylation and fibronectin synthesis in human and murine lupus and the effect of mycophenolic acid. Arthritis Rheum 2009; 60: 2071-2082 [impact factor: 7.866, citations: 7].

6. Yung S, Tsang RC, Leung JK, Chan TM. Increased mesangial cell hyaluronan expression in lupus nephritis is mediated by anti-DNA antibody-induced IL-1beta. Kidney Int 2006; 69: 272-280 [impact factor: 6.606, citations: 11].

7. Yung S, Tsang RC, Sun Y, Leung JK, Chan TM. Effect of human anti-DNA antibodies on proximal renal tubular epithelial cell cytokine expression: implications on tubulointerstitial inflammation in lupus nephritis. J Am Soc Nephrol 2005; 16: 3281-3294 [impact factor: 9.663, citations: 14].

8. Yung S, Chen XR, Tsang RC, Zhang Q, Chan TM. Reduction of perlecan synthesis and induction of TGF-beta1 in human peritoneal mesothelial cells due to high dialysate glucose concentration: implication in peritoneal dialysis. J Am Soc Nephrol 2004; 15: 1178-1188 [impact factor: 9.663, citations: 16].
   
   
   
   

Key Offices